199025355 Union Ball Valve Industrial Water Treatment PVC 150PSI Corrosion-Resistant Valve

1. Pharma-Grade Mass Flow & Density Measurement Solution​

The GF Signet 199025355 Proline is an ultra-hygienic Coriolis flowmeter engineered for precision measurement in pharmaceutical and biotechnology applications requiring EHEDG EL-Class I compliance. Featuring ​full-bore PFA lining​ and ​platinum-coated flow tubes, this device delivers ​​±0.05% mass flow accuracy​ and ​​±0.0005g/cm³ density resolution​ across ​0–80 t/h ranges​ with ​​≤50ms response time. Its ​IP69K-rated 316L stainless steel housing​ withstands ​150°C SIP cycles​ and ​100-bar CIP cleaning​ while meeting ​ASME BPE-2022 Ra≤0.4µm standards. The "25355" suffix denotes ​DN80 tri-clamp connection, ​PROFIsafe + WirelessHART outputs, and ​SIL 3 compliance​ per IEC 61508. Certified for ​​-40°C to +150°C operation, it incorporates ​FDA 21 CFR 177.2600 materials​ with ​crevice-free flow path​ and ​3° self-draining slope. Designed for vaccine production lines and single-use bioreactors, this transmitter enables ​bubble-tolerant measurement​ of shear-sensitive media with ​auto-validation reporting​ via integrated Heartbeat Technology®.

​2. Critical Applications & Technical Advantages​

This Coriolis meter excels in mission-critical processes including ​monoclonal antibody harvest verification​ (±0.5% accuracy), ​perfusion bioreactor media control​ (0.1–30 L/min), and ​sterile vial filling​ (±0.2mL volume accuracy). Key advantages include ​Heartbeat Technology®​ for automated in-situ verification without process interruption, ​real-time tube health monitoring​ via natural frequency shift analysis (0.1Hz resolution), and ​predictive maintenance alerts​ for coating accumulation (>0.03mm). The DN80 tri-clamp connections enable rapid changeover between campaigns in GMP environments, while SIL 3 certification supports safety instrumented functions for overfill prevention in single-use bioreactors. With ​**>25-year operational lifespan​ and ​10-year calibration stability**, it provides ​Pharma 4.0 integration​ via OPC UA/MQTT protocols for real-time MES connectivity and automated FDA 21 CFR Part 11 audit trails.

​3. Advanced Functionality & Compliance​

​Measurement Integrity​ utilizes ​dual-curve Coriolis technology​ achieving ​0.05% accuracy​ through temperature-compensated phase shift analysis. ​Safety Functions​ include ​SIL 3 overfill prevention​ with independent trip circuit (≤50ms response) and ​fail-safe state​ forcing 22mA output during critical faults. ​Predictive Diagnostics​ analyze ​tube fatigue rates​ via natural frequency trending and ​coating accumulation​ through drive current monitoring. ​Compliance Tools​ generate ​automated validation packages​ per GAMP 5, ​SEMI E142 formatted data​ for continuous process verification, and ​electronic calibration records​ with NIST traceability. The transmitter's ​gold-plated electronics​ ensure long-term signal integrity, while ​conformal-coated PCBs​ resist corrosive CIP chemicals like PAA and HNO₃.

 
 
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Company Information
Xiamen ZhiCheng Automation Technology Co., Ltdit is a leading global supplier of control system components. We specialize in control systems and drives.
With many years of experience in the industrial sector, we consistently deliver the highest quality of spare parts.which make sure that all this jobs are
 
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